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Interleukin 7 Receptor (IL7R) Peptid

IL7R Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN938111
  • Target Alle IL7R Produkte
    IL7R (Interleukin 7 Receptor (IL7R))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    ESFLDCQIHR VDDIQARDEV EGFLQDTFPQ QLEESEKQRL GGDVQSPNCP
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of IL7 R antibody,
    Alternative Names: IL7R control peptide, IL7R antibody Blocking Peptide, Anti-IL7R Blocking Peptide, interleukin 7 receptor Blocking Peptide, CD127 Blocking Peptide, CDW127 Blocking Peptide, IL-7R-alpha Blocking Peptide, IL7RA Blocking Peptide, ILRA Blocking Peptide, IL7R, ILR-7, ILR 7, ILR-7 Blocking Peptide, ILR 7 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    IL7R (Interleukin 7 Receptor (IL7R))
    Synonyme
    IL7R Peptide, CD127 Peptide, IL-7Ralpha Peptide, CDW127 Peptide, IL-7R-alpha Peptide, IL7RA Peptide, ILRA Peptide, IL-7RA Peptide, interleukin 7 receptor Peptide, IL7R Peptide, Il7r Peptide
    Hintergrund
    The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
    Molekulargewicht
    49 kDa
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