A synthetic peptide for use as a blocking control in assays to test for specificity of SHB antibody, Alternative Names: SHB control peptide, SHB antibody Blocking Peptide, Anti-SHB Blocking Peptide, Src Homology 2 Domain Containing Adaptor Protein B Blocking Peptide, RP.8 Blocking Peptide, bA3J10.2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
SHB
(Src Homology 2 Domain Containing Adaptor Protein B (SHB))
Hintergrund
SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.