A synthetic peptide for use as a blocking control in assays to test for specificity of CDH4 antibody, Alternative Names: CDH4 control peptide, CDH4 antibody Blocking Peptide, Anti-CDH4 Blocking Peptide, Cadherin 4 Type 1 Blocking Peptide, R-Cadherin Blocking Peptide, CAD4 Blocking Peptide, FLJ22202 Blocking Peptide, FLJ40547 Blocking Peptide, MGC126700 Blocking Peptide, MGC138355 Blocking Peptide, RCAD Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
Cadherin 4 (CDH4)
Hintergrund
CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.