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Tetratricopeptide Repeat Domain 8 (TTC8) Peptid

TTC8 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937985
  • Target Alle TTC8 Produkte
    TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT GFLRPSTQSG
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of TTC8 antibody,
    Alternative Names: TTC8 control peptide, TTC8 antibody Blocking Peptide, Anti-TTC8 Blocking Peptide, Tetratricopeptide Repeat Domain 8 Blocking Peptide, BBS8 Blocking Peptide, TTC8, TTC-8, TTC 8, TTC-8 Blocking Peptide, TTC 8 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))
    Hintergrund
    The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.
    Molekulargewicht
    54 kDa
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