A synthetic peptide for use as a blocking control in assays to test for specificity of NPTX2 antibody, Alternative Names: NPTX2 control peptide, NPTX2 antibody Blocking Peptide, Anti-NPTX2 Blocking Peptide, neuronal pentraxin II Blocking Peptide, NARP Blocking Peptide, NP-II Blocking Peptide, NP2 Blocking Peptide, NPTX2, NPTX-2, NPTX 2, NPTX-2 Blocking Peptide, NPTX 2 Blocking Peptide
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
NPTX2
(Neuronal Pentraxin II (NPTX2))
Hintergrund
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.