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Periplakin (PPL) Peptid

PPL Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937909
  • Target Alle PPL Produkte
    PPL (Periplakin (PPL))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    EKSRAQEKVT EKEVVKLQND PQLEAEYQQL QEDHQRQDQL REKQEEELSF
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of PPL antibody,
    Alternative Names: Periplakin control peptide, Periplakin antibody Blocking Peptide, Anti-Periplakin Blocking Peptide, KIAA0568 Blocking Peptide, MGC134872 Blocking Peptide, PPL Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    PPL (Periplakin (PPL))
    Hintergrund
    PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
    Molekulargewicht
    205 kDa
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