A synthetic peptide for use as a blocking control in assays to test for specificity of FKBP3 antibody, Alternative Names: FKBP3 control peptide, FKBP3 antibody Blocking Peptide, Anti-FKBP3 Blocking Peptide, Fk506 Binding Protein 3 25Kda Blocking Peptide, FKBP-25 Blocking Peptide, PPIase Blocking Peptide, FK506, FK-506, FK 506, FK-506 Blocking Peptide, FK 506 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
FKBP3
(FK506 Binding Protein 3, 25kDa (FKBP3))
Hintergrund
FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.