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Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1) Peptid

PSMF1 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937624

Kurzübersicht für Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1) Peptid (ABIN937624)

Target

PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Spezies

Säugetier

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    DYIDAEHLGD FHRTYKNSEE LRSRIVSGII TPIHEQWEKA NVSSPHREFP

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of PSMF1 antibody,
    Alternative Names: PSMF1 control peptide, PSMF1 antibody Blocking Peptide, Anti-PSMF1 Blocking Peptide, proteasome, prosome, macropain inhibitor subunit 1, PI31 Blocking Peptide, PI31 Blocking Peptide, PSMF1, PSMF-1, PSMF 1, PSMF-1 Blocking Peptide, PSMF 1 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

    Hintergrund

    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.

    Molekulargewicht

    30 kDa
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