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MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Peptid

MRE11A Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937579

Kurzübersicht für MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Peptid (ABIN937579)

Target

Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Spezies

Säugetier

Quelle

  • 8
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    DTFVTLDEIL RLAQENEVDF ILLGGDLFHE NKPSRKTLHT CLELLRKYCM

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of MRE11 A antibody,
    Alternative Names: MRE11A control peptide, MRE11A antibody Blocking Peptide, Anti-MRE11A Blocking Peptide, MRE11 meiotic recombination 11 homolog A, S. cerevisiae Blocking Peptide, ATLD Blocking Peptide, HNGS1 Blocking Peptide, MRE11 Blocking Peptide, MRE11B Blocking Peptide, MRE11A, MREA-11, MREA 11, MREA-11 Blocking Peptide, MREA 11 Blocking Peptide

    Aufreinigung

    The antibody is affinity purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

    Hintergrund

    This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

    Molekulargewicht

    80 kDa
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