Runt-Related Transcription Factor 2 (RUNX2) Peptid
RUNX2
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN937574
Kurzübersicht für Runt-Related Transcription Factor 2 (RUNX2) Peptid (ABIN937574)
Target
RUNX2
(Runt-Related Transcription Factor 2 (RUNX2))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- DTATSDFCLW PSTLSKKSQA GASELGPFSD PRQFPSISSL TESRFSNPRM
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of RUNX2 antibody,
Alternative Names: RUNX2 control peptide, RUNX2 antibody Blocking Peptide, Anti-RUNX2 Blocking Peptide, Runt-Related Transcription Factor 2 Blocking Peptide, RUNX2, RUNX-2, RUNX 2, RUNX-2 Blocking Peptide, RUNX 2 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Hintergrund
- RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.
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Molekulargewicht
- 57 kDa
Target
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