A synthetic peptide for use as a blocking control in assays to test for specificity of IGF1 R antibody, Alternative Names: IGF1R control peptide, IGF1R antibody Blocking Peptide, Anti-IGF1R Blocking Peptide, insulin-like growth factor 1 receptor Blocking Peptide, CD221 Blocking Peptide, IGFIR Blocking Peptide, JTK13 Blocking Peptide, MGC142170 Blocking Peptide, MGC142172 Blocking Peptide, MGC18216 Blocking Peptide, IGF1R, IGFR-1, IGFR 1, IGFR-1 Blocking Peptide, IGFR 1 Blocking Peptide
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.