Norrie Disease (Pseudoglioma) (NDP) Peptid
NDP
Reaktivität: Säugetier
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN937500
382,12 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 20 bis 27 Werktagen
Kurzübersicht für Norrie Disease (Pseudoglioma) (NDP) Peptid (ABIN937500)
Target
Norrie Disease (Pseudoglioma) (NDP)
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Protein-Typ
- Synthetic
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Sequenz
- DPRRCMRHHY VDSISHPLYK CSSKMVLLAR CEGHCSQASR SEPLVSFSTV
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of NDP antibody,
Alternative Names: NDP control peptide, NDP antibody Blocking Peptide, Anti-NDP Blocking Peptide, Norrie Disease Blocking Peptide, Pseudoglioma Blocking Peptide, EVR2 Blocking Peptide, FEVR Blocking Peptide, ND Blocking Peptide -
Aufreinigung
- Rabbit Anti-p44/42 MAP Kinase (Ab-202) Polyclonal Antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- Norrie Disease (Pseudoglioma) (NDP)
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Hintergrund
- NDP activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. NDP plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. NDP acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1).
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Molekulargewicht
- 15 kDa
Target
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