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Transmembrane Protein 173 (TMEM173) Peptid

TMEM173 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC

Produktnummer ABIN937495

Kurzübersicht für Transmembrane Protein 173 (TMEM173) Peptid (ABIN937495)

Target

STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Spezies

Säugetier

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)

Protein-Typ

Synthetic

Sequenz

DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL

Produktmerkmale

A synthetic peptide for use as a blocking control in assays to test for specificity of TMEM173 antibody,
Alternative Names: TMEM173 control peptide, TMEM173 antibody Blocking Peptide, Anti-TMEM173 Blocking Peptide, Transmembrane Protein 173 Blocking Peptide, FLJ38577 Blocking Peptide, TMEM173, TMEM-173, TMEM 173, TMEM-173 Blocking Peptide, TMEM 173 Blocking Peptide
Transmembrane Protein 173 (TMEM173) (Middle Region) peptide
TMEM173 Reaktivität: Human Wirt: Synthetic BP, WB

Transmembrane Protein 173 (TMEM173) (C-Term) peptide
TMEM173 Reaktivität: Human, Ratte Wirt: Synthetic BP, WB

Transmembrane Protein 173 (TMEM173) (C-Term) peptide
TMEM173 Reaktivität: Human BP Sodium azide

Transmembrane Protein 173 (TMEM173) peptide
TMEM173 Reaktivität: Human, Ratte, Maus Wirt: Synthetic BP, WB, ICo, IDe

Transmembrane Protein 173 (TMEM173) peptide
TMEM173 Reaktivität: Human Wirt: Synthetic BP

Applikationshinweise

Optimal conditions should be determined by the investigator

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

Buffer

PBS

Handhabung

Avoid repeated freeze/thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C long term.
Target

STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Hintergrund

TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

Molekulargewicht

42 kDa

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