Transmembrane Protein 173 (TMEM173) Peptid
TMEM173
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
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- Target Alle STING/TMEM173 (TMEM173) Produkte
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Protein-Typ
- Synthetic
- Spezies
- Säugetier
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
- Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of TMEM173 antibody,
Alternative Names: TMEM173 control peptide, TMEM173 antibody Blocking Peptide, Anti-TMEM173 Blocking Peptide, Transmembrane Protein 173 Blocking Peptide, FLJ38577 Blocking Peptide, TMEM173, TMEM-173, TMEM 173, TMEM-173 Blocking Peptide, TMEM 173 Blocking Peptide
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- Applikationshinweise
- Optimal conditions should be determined by the investigator
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C long term.
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- Target
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Hintergrund
- TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
- Molekulargewicht
- 42 kDa
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