A synthetic peptide for use as a blocking control in assays to test for specificity of ATG5 antibody, Alternative Names: ATG5 control peptide, ATG5 antibody Blocking Peptide, Anti-ATG5 Blocking Peptide, Atg5 Autophagy Related 5 Homolog Blocking Peptide, APG5 Blocking Peptide, APG5L Blocking Peptide, ASP Blocking Peptide, hAPG5 Blocking Peptide, ATG5, ATG-5, ATG 5, ATG-5 Blocking Peptide, ATG 5 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
ATG5
(ATG5 Autophagy Related 5 (ATG5))
Hintergrund
ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.