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Interleukin 1, beta (IL1B) Peptid

IL1B Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937423

Kurzübersicht für Interleukin 1, beta (IL1B) Peptid (ABIN937423)

Target

IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Spezies

Säugetier

Quelle

  • 13
  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    DLDLCPLDGG IQLRISDHHY SKGFRQAASV VVAMDKLRKM LVPCPQTFQE

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of IL1 B antibody,
    Alternative Names: IL1 beta control peptide, IL1 beta antibody Blocking Peptide, Anti-IL1 beta Blocking Peptide, Interleukin 1 Beta Blocking Peptide, IL-1 Blocking Peptide, IL1-BETA Blocking Peptide, IL1F2 Blocking Peptide, IL1B Blocking Peptide, IL1 beta, IL beta-1, IL beta 1, IL beta-1 Blocking Peptide, IL beta 1 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

    Hintergrund

    IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

    Molekulargewicht

    17 kDa
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