A synthetic peptide for use as a blocking control in assays to test for specificity of ADD3 antibody, Alternative Names: ADD3 control peptide, ADD3 antibody Blocking Peptide, Anti-ADD3 Blocking Peptide, adducin 3, gamma Blocking Peptide, ADDL Blocking Peptide, ADD3, ADD-3, ADD 3, ADD-3 Blocking Peptide, ADD 3 Blocking Peptide
ADD3
Reaktivität: Human, Rind (Kuh), Maus, Ratte
Wirt: Synthetic
BP
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
ADD3
(Adducin 3 (Gamma) (ADD3))
Hintergrund
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues.sPolymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains.