Methyl-CpG Binding Domain Protein 2 (MBD2) Peptid
MBD2
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN937259
Kurzübersicht für Methyl-CpG Binding Domain Protein 2 (MBD2) Peptid (ABIN937259)
Target
MBD2
(Methyl-CpG Binding Domain Protein 2 (MBD2))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- DCPALPPGWK KEEVIRKSGL SAGKSDVYYF SPSGKKFRSK PQLARYLGNT
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of MBD2 antibody,
Alternative Names: MBD2 control peptide, MBD2 antibody Blocking Peptide, Anti-MBD2 Blocking Peptide, Methyl-Cpg Binding Domain Protein 2 Blocking Peptide, MBD2, MBD-2, MBD 2, MBD-2 Blocking Peptide, MBD 2 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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Hintergrund
- MBD2 belongs to a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MBD2 can also repress transcription from methylated gene promoters. MBD2 may function as a mediator of the biological consequences of the methylation signal. It is also reported that the MBD2 functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development.
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Molekulargewicht
- 32 kDa
Target
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