A synthetic peptide for use as a blocking control in assays to test for specificity of PBEF1 antibody, Alternative Names: PBEF1 control peptide, PBEF1 antibody Blocking Peptide, Anti-PBEF1 Blocking Peptide, Pre-B-Cell Colony Enhancing Factor 1 Blocking Peptide, 1110035O14Rik Blocking Peptide, DKFZP666B131 Blocking Peptide, MGC117256 Blocking Peptide, NAMPT Blocking Peptide, PBEF Blocking Peptide, PBEF1, PBEF-1, PBEF 1, PBEF-1 Blocking Peptide, PBEF 1 Blocking Peptide
PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.