A synthetic peptide for use as a blocking control in assays to test for specificity of CTCFL antibody, Alternative Names: CTCFL control peptide, CTCFL antibody Blocking Peptide, Anti-CTCFL Blocking Peptide, CCCTC-binding factor, zinc finger protein-like Blocking Peptide, BORIS Blocking Peptide, CTCF-T Blocking Peptide, MGC163358 Blocking Peptide, dJ579F20.2 Blocking Peptide
BORIS Peptide, CT27 Peptide, CTCF-T Peptide, HMGB1L1 Peptide, dJ579F20.2 Peptide, CTCFL Peptide, Boris Peptide, OTTMUSG00000016680 Peptide, CCCTC-binding factor like Peptide, CCCTC-binding factor (zinc finger protein)-like Peptide, CTCFL Peptide, Ctcfl Peptide
Hintergrund
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.