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NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1) Peptid

NKIRAS1 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937066
  • Target Alle NKIRAS1 Produkte
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    CETMEDVYMA SVETDRGVKE QLHLYDTRGL QEGVELPKHY FSFADGFVLV
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of NKIRAS1 antibody,
    Alternative Names: NKIRAS1 control peptide, NKIRAS1 antibody Blocking Peptide, Anti-NKIRAS1 Blocking Peptide, Nfkb Inhibitor Interacting Ras-Like 1 Blocking Peptide, KBRAS1 Blocking Peptide, kappaB-Ras1 Blocking Peptide, NKIRAS1, NKIRAS-1, NKIRAS 1, NKIRAS-1 Blocking Peptide, NKIRAS 1 Blocking Peptide
    Aufreinigung
    The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    Synonyme
    NKIRAS1 Peptide, KBRAS1 Peptide, kappaB-Ras1 Peptide, zgc:92823 Peptide, kbras1 Peptide, 2400004O09Rik Peptide, NFKB inhibitor interacting Ras like 1 Peptide, NFKB inhibitor interacting Ras-like 1 Peptide, NFKB inhibitor interacting Ras-like 1 S homeolog Peptide, NFKB inhibitor interacting Ras-like protein 1 Peptide, NKIRAS1 Peptide, nkiras1 Peptide, nkiras1.S Peptide, Nkiras1 Peptide
    Hintergrund
    NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
    Molekulargewicht
    22 kDa
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