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KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3 (kDELR3) Peptid

kDELR3 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937021
  • Target Alle KDELR3 (kDELR3) Produkte
    KDELR3 (kDELR3) (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3 (kDELR3))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    AYVTVYMIYG KFRKTFDSEN DTFRLEFLLV PVIGLSFLEN YSFTLLEILW
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of KDELR3 antibody,
    Alternative Names: KDELR3 control peptide, KDELR3 antibody Blocking Peptide, Anti-KDELR3 Blocking Peptide, Kdel Blocking Peptide, Lys-Asp-Glu-Leu Endoplasmic Reticulum Protein Retention Receptor 3 Blocking Peptide, ERD2L3 Blocking Peptide, KDELR3, KDELR-3, KDELR 3, KDELR-3 Blocking Peptide, KDELR 3 Blocking Peptide
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    KDELR3 (kDELR3) (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3 (kDELR3))
    Synonyme
    ERD2L3 Peptide, AI173274 Peptide, ERD2 Peptide, kdelr Peptide, KDEL endoplasmic reticulum protein retention receptor 3 Peptide, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 Peptide, KDEL endoplasmic reticulum protein retention receptor 3 L homeolog Peptide, KDELR3 Peptide, Kdelr3 Peptide, kdelr3.L Peptide
    Hintergrund
    Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (kDaEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognises, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the kDaEL receptor gene family, have been described. kDaELR3 was the third member of the family to be identified, and it encodes a protein highly homologous to kDaELR1 and kDaELR2 proteins.
    Molekulargewicht
    25 kDa
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