Crossover junction endonuclease EME1 (EME1) Peptid
EME1
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN937018
Kurzübersicht für Crossover junction endonuclease EME1 (EME1) Peptid (ABIN937018)
Target
Crossover junction endonuclease EME1 (EME1)
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Protein-Typ
- Synthetic
-
Sequenz
- AYPSPQLLVQ AYQQCFSDKE RQNLLADIQV RRGEGVTSTS RRIGPELSRR
-
Produktmerkmale
-
A synthetic peptide for use as a blocking control in assays to test for specificity of EME1 antibody,
Alternative Names: EME1 control peptide, EME1 antibody Blocking Peptide, Anti-EME1 Blocking Peptide, Essential Meiotic Endonuclease 1 Homolog 1 Blocking Peptide, FLJ31364 Blocking Peptide, MMS4L Blocking Peptide, EME1, EME-1, EME 1, EME-1 Blocking Peptide, EME 1 Blocking Peptide
-
-
-
-
Applikationshinweise
- Optimal conditions should be determined by the investigator
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handhabung
- Avoid repeated freeze/thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C long term.
-
-
- Crossover junction endonuclease EME1 (EME1)
-
Hintergrund
- EME1 interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. EME1 may be required in mitosis for the processing of stalled or collapsed replication forks.EME1 and MUS81 form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication.
-
Molekulargewicht
- 63 kDa
Target
-
Sie sind hier:
