Signal Transducer and Activator of Transcription 5B (STAT5B) Peptid
Kurzübersicht für Signal Transducer and Activator of Transcription 5B (STAT5B) Peptid (ABIN937008)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- AVWIQAQQLQ GEALHQMQAL YGQHFPIEVR HYLSQWIESQ AWDSVDLDNP
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of STAT5 B antibody,
Alternative Names: STAT5B control peptide, STAT5B antibody Blocking Peptide, Anti-STAT5B Blocking Peptide, signal transducer and activator of transcription 5B Blocking Peptide, STAT5 Blocking Peptide, STAT5B, STATB-5, STATB 5, STATB-5 Blocking Peptide, STATB 5 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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Hintergrund
- The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
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Molekulargewicht
- 90 kDa
Target
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