A synthetic peptide for use as a blocking control in assays to test for specificity of UPB1 antibody, Alternative Names: UPB1 control peptide, UPB1 antibody Blocking Peptide, Anti-UPB1 Blocking Peptide, Ureidopropionase Beta Blocking Peptide, BUP1 Blocking Peptide, UPB1, UPB-1, UPB 1, UPB-1 Blocking Peptide, UPB 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
UPB1
(Ureidopropionase, beta (UPB1))
Hintergrund
UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.