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8-Oxoguanine DNA Glycosylase (OGG1) Peptid

OGG1 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN936997
  • Target Alle OGG1 Produkte
    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of OGG1 antibody,
    Alternative Names: OGG1 control peptide, OGG1 antibody Blocking Peptide, Anti-OGG1 Blocking Peptide, 8-oxoguanine DNA glycosylase Blocking Peptide, HMMH Blocking Peptide, HOGG1 Blocking Peptide, MUTM Blocking Peptide, OGH1 Blocking Peptide, OGG1, OGG-1, OGG 1, OGG-1 Blocking Peptide, OGG 1 Blocking Peptide
    Aufreinigung
    Protein A affinity column
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
    Hintergrund
    This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.
    Molekulargewicht
    35 kDa
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