A synthetic peptide for use as a blocking control in assays to test for specificity of EGLN2 antibody, Alternative Names: EGLN2 control peptide, EGLN2 antibody Blocking Peptide, Anti-EGLN2 Blocking Peptide, egl nine homolog 2, C. elegans Blocking Peptide, DKFZp434E026 Blocking Peptide, EIT6 Blocking Peptide, HIFPH1 Blocking Peptide, HPH-3 Blocking Peptide, PHD1 Blocking Peptide, EGLN2, EGLN-2, EGLN 2, EGLN-2 Blocking Peptide, EGLN 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PHD1 (EGLN2)
(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
Hintergrund
The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms. The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation.