A synthetic peptide for use as a blocking control in assays to test for specificity of CCDC139 antibody, Alternative Names: PUS10 control peptide, PUS10 antibody Blocking Peptide, Anti-PUS10 Blocking Peptide, Pseudouridylate Synthase 10 Blocking Peptide, FLJ32312 Blocking Peptide, MGC126729 Blocking Peptide, MGC126755 Blocking Peptide, PUS10, PUS-10, PUS 10, PUS-10 Blocking Peptide, PUS 10 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PUS10
(Pseudouridylate Synthase 10 (PUS10))
Hintergrund
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs.