A synthetic peptide for use as a blocking control in assays to test for specificity of DCK antibody, Alternative Names: DCK control peptide, DCK antibody Blocking Peptide, Anti-DCK Blocking Peptide, Deoxycytidine Kinase Blocking Peptide, MGC117410 Blocking Peptide, MGC138632 Blocking Peptide
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.