Ribonucleotide Reductase M1 (RRM1) Peptid
Kurzübersicht für Ribonucleotide Reductase M1 (RRM1) Peptid (ABIN936944)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- ATGSYIAGTN GNSNGLVPML RVYNNTARYV DQGGNKRPGA FAIYLEPWHL
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of RRM1 antibody,
Alternative Names: RRM1 control peptide, RRM1 antibody Blocking Peptide, Anti-RRM1 Blocking Peptide, Ribonucleotide Reductase M1 Polypeptide Blocking Peptide, R1 Blocking Peptide, RIR1 Blocking Peptide, RR1 Blocking Peptide, RRM1, RRM-1, RRM 1, RRM-1 Blocking Peptide, RRM 1 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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Hintergrund
- RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Its gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Its gene may play a role in malignancies and disease that involve this region.
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Molekulargewicht
- 90 kDa
Target
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