Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Peptid
PCMT1
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN936828
Kurzübersicht für Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1) Peptid (ABIN936828)
Target
PCMT1
(Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- APYDAIHVGA AAPVVPQALI DQLKPGGRLI LPVGPAGGNQ MLEQYDKLQD
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of PCMT1 antibody,
Alternative Names: PCMT1 control peptide, PCMT1 antibody Blocking Peptide, Anti-PCMT1 Blocking Peptide, Protein-L-Isoaspartate Blocking Peptide, D-Aspartate O-Methyltransferase Blocking Peptide, PCMT1, PCMT-1, PCMT 1, PCMT-1 Blocking Peptide, PCMT 1 Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))
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Hintergrund
- Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.
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Molekulargewicht
- 25 kDa
Target
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