RE1-Silencing Transcription Factor (REST) Peptid
REST
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
-
- Target Alle REST Produkte
- REST (RE1-Silencing Transcription Factor (REST))
- Protein-Typ
- Synthetic
- Spezies
- Säugetier
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- ANMGMALTND MYDLHELSKA ELAAPQLIML ANVALTGEAS GSCCDYLVGE
- Produktmerkmale
-
A synthetic peptide for use as a blocking control in assays to test for specificity of Rest antibody,
Alternative Names: Rest control peptide, Rest antibody Blocking Peptide, Anti-Rest Blocking Peptide, RE1-silencing transcription factor Blocking Peptide, 2610008J04Rik Blocking Peptide, AA407358 Blocking Peptide, MGC150099 Blocking Peptide, NRSF Blocking Peptide
-
-
- Applikationshinweise
- Optimal conditions should be determined by the investigator
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C long term.
-
- Target
- REST (RE1-Silencing Transcription Factor (REST))
- Hintergrund
- Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
- Molekulargewicht
- 118 kDa
-
Sie sind hier:
