A synthetic peptide for use as a blocking control in assays to test for specificity of PRAME antibody, Alternative Names: PRAME control peptide, PRAME antibody Blocking Peptide, Anti-PRAME Blocking Peptide, Preferentially Expressed Antigen In Melanoma Blocking Peptide, MAPE Blocking Peptide, OIP4 Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
PRAME
(Preferentially Expressed Antigen in Melanoma (PRAME))
Hintergrund
PRAME functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. PRAME prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.