A synthetic peptide for use as a blocking control in assays to test for specificity of TNIP1 antibody, Alternative Names: TNIP1 control peptide, TNIP1 antibody Blocking Peptide, Anti-TNIP1 Blocking Peptide, TNFAIP3 interacting protein 1 Blocking Peptide, ABIN-1 Blocking Peptide, KIAA0113 Blocking Peptide, NAF1 Blocking Peptide, VAN Blocking Peptide, TNIP1, TNIP-1, TNIP 1, TNIP-1 Blocking Peptide, TNIP 1 Blocking Peptide
TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4(T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.