A synthetic peptide for use as a blocking control in assays to test for specificity of ARFGAP3 antibody, Alternative Names: ARFGAP3 control peptide, ARFGAP3 antibody Blocking Peptide, Anti-ARFGAP3 Blocking Peptide, ADP-ribosylation factor GTPase activating protein 3 Blocking Peptide, ARFGAP1 Blocking Peptide, FLJ45618 Blocking Peptide, ARFGAP3, ARFGAP-3, ARFGAP 3, ARFGAP-3 Blocking Peptide, ARFGAP 3 Blocking Peptide
Aufreinigung
This product was prepared from monospecific antiserum by delipidation, saltfractionation and ion exchange chromatography. Anti-RFX5 (N-terminal specific) may react with unknown minorbands at 55 kDa and 85 kDa.
ARFGAP3
Reaktivität: Human, Maus
Wirt: Synthetic
BP, BI
Applikationshinweise
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
ARFGAP3
(ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
Hintergrund
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.