A synthetic peptide for use as a blocking control in assays to test for specificity of GBA antibody, Alternative Names: GBA control peptide, GBA antibody Blocking Peptide, Anti-GBA Blocking Peptide, glucosidase, beta, acid Blocking Peptide, GBA1 Blocking Peptide, GCB Blocking Peptide, GLUC Blocking Peptide
Optimal conditions should be determined by the investigator
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20 °C long term.
Target
GBA
(Glucosidase, Beta, Acid (GBA))
Hintergrund
This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.