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Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) Peptid

PARK2 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN936245
  • Target Alle Parkin (PARK2) Produkte
    Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
    Protein-Typ
    Synthetic
    Spezies
    Säugetier
    Quelle
    • 8
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    YTRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEQGQRKVT CEGGNGLGCG
    Produktmerkmale
    A synthetic peptide for use as a blocking control in assays to test for specificity of Park2 antibody,
    Alternative Names: Park2 control peptide, Park2 antibody Blocking Peptide, Anti-Park2 Blocking Peptide, Parkinson disease, autosomal recessive, juvenile 2, parkin Blocking Peptide, MGC130518 Blocking Peptide, PRKN Blocking Peptide, Park2, Park-2, Park 2, Park-2 Blocking Peptide, Park 2 Blocking Peptide
    Aufreinigung
    Serum
  • Applikationshinweise
    Optimal conditions should be determined by the investigator
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C long term.
  • Target
    Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
    Hintergrund
    Park2 functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include SYT11, CCNE1, GPR37, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5 and AIMP2. Park2 may play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. Park2 limits the production of reactive oxygen species (ROS).
    Molekulargewicht
    51 kDa
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