Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptid
Kurzübersicht für Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptid (ABIN936209)
Target
Spezies
Quelle
Applikation
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Protein-Typ
- Synthetic
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Sequenz
- YRWMIDSRDD FTEERLAKLQ DPFSLYRCHT IMNCTRTCPK GLNPGKAIAE
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of SDHB antibody,
Alternative Names: SDHB control peptide, SDHB antibody Blocking Peptide, Anti-SDHB Blocking Peptide, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Blocking Peptide, IP Blocking Peptide, PGL4 Blocking Peptide, SDH Blocking Peptide, SDH1 Blocking Peptide, SDHIP Blocking Peptide
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
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Hintergrund
- Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
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Molekulargewicht
- 31 kDa
Target
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