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Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptid

SDHB Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN936209
382,12 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 20 bis 27 Werktagen

Kurzübersicht für Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) Peptid (ABIN936209)

Target

SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Spezies

Säugetier

Quelle

  • 6
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    YRWMIDSRDD FTEERLAKLQ DPFSLYRCHT IMNCTRTCPK GLNPGKAIAE

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of SDHB antibody,
    Alternative Names: SDHB control peptide, SDHB antibody Blocking Peptide, Anti-SDHB Blocking Peptide, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Blocking Peptide, IP Blocking Peptide, PGL4 Blocking Peptide, SDH Blocking Peptide, SDH1 Blocking Peptide, SDHIP Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

    Hintergrund

    Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

    Molekulargewicht

    31 kDa
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