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Adrenergic, alpha-1B-, Receptor (ADRA1B) Peptid

ADRA1B Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN936205

Kurzübersicht für Adrenergic, alpha-1B-, Receptor (ADRA1B) Peptid (ABIN936205)

Target

ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

Spezies

Säugetier

Quelle

  • 9
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    YRPWTRGGSL ERSQSRKDSL DDSGSCLSGS QRTLPSASPS PGYLGRGAPP

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of ADRA1 B antibody,
    Alternative Names: ADRA1B control peptide, ADRA1B antibody Blocking Peptide, Anti-ADRA1B Blocking Peptide, adrenergic, alpha-1B-, receptor Blocking Peptide, ADRA1 Blocking Peptide, ALPHA1BAR Blocking Peptide, ADRA1B, ADRAB-1, ADRAB 1, ADRAB-1 Blocking Peptide, ADRAB 1 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

    Hintergrund

    Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

    Molekulargewicht

    57 kDa
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