A synthetic peptide for use as a blocking control in assays to test for specificity of LYCAT antibody, Alternative Names: LYCAT control peptide, LYCAT antibody Blocking Peptide, Anti-LYCAT Blocking Peptide, Lysocardiolipin Acyltransferase Blocking Peptide, ALCAT1 Blocking Peptide, FLJ37965 Blocking Peptide, UNQ1849 Blocking Peptide
LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognises both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.