Retinoic Acid Receptor, alpha (RARA) Peptid
RARA
Reaktivität: Säugetier
Wirt: Synthetic
BP, WB, IHC
Produktnummer ABIN936051
Kurzübersicht für Retinoic Acid Receptor, alpha (RARA) Peptid (ABIN936051)
Target
Retinoic Acid Receptor alpha (RARA)
(Retinoic Acid Receptor, alpha (RARA))
Spezies
Säugetier
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein-Typ
- Synthetic
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Sequenz
- YESVEVGGPT PNPFLVVDFY NQNRACLLPE KGLPAPGPYS TPLRTPLWNG
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Produktmerkmale
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A synthetic peptide for use as a blocking control in assays to test for specificity of RARA antibody,
Alternative Names: RARA control peptide, RARA antibody Blocking Peptide, Anti-RARA Blocking Peptide, Retinoic Acid Receptor Alpha Blocking Peptide, NR1B1 Blocking Peptide, RAR Blocking Peptide
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Retinoic Acid Receptor, alpha (RARA) peptide
RARA Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal conditions should be determined by the investigator
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C long term.
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- Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
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Hintergrund
- Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
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Molekulargewicht
- 51 kDa
Target
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