PINK1
Reaktivität: Human, Ratte
Wirt: Synthetic
BP, BI
Applikationshinweise
PINK1 protein has been used in SDS-PAGE, and may be suitable for use in other applications
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) 1 M Urea, 5 % Glycerol.
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
4 °C/-20 °C/-80 °C
Informationen zur Lagerung
Can be stored at 4 °C short term (1-2 weeks). For long term storage, aliquot and store at -20 °C or -70 °C.
Target
PINK1
(PTEN Induced Putative Kinase 1 (PINK1))
Hintergrund
PINK1 is a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this protein cause one form of autosomal recessive early-onset Parkinson disease. Recombinant human PINK protein was expressed in E.coli and purified by using conventional chromatography techniques. Alternative Names: FLJ27236 protein, PINK1, PINK 1, PARK6 protein, Serine/threonine-protein kinase PINK1 protein, PINK 1 protein, PINK-1 protein, PINK-1, mitochondrial protein, BRPK protein