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Transthyretin (TTR) (AA 21-147) Peptid

TTR Reaktivität: Human Wirt: Escherichia coli (E. coli) SDS
Produktnummer ABIN935081

Kurzübersicht für Transthyretin (TTR) (AA 21-147) Peptid (ABIN935081)

Target

TTR (Transthyretin (TTR))

Spezies

Human

Quelle

  • 4
Escherichia coli (E. coli)

Applikation

SDS-PAGE (SDS)
  • Protein-Typ

    Recombinant

    Protein Region

    AA 21-147

    Sequenz

    MGPTGTGESK CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT TEEEFVEGIY KVEIDTKSYW KALGISPFHE HAEVVFTAND SGPRRYTIAA LLSPYSYSTT AVVTNPKE

    Produktmerkmale

    Purified recombinant Human Prealbumin protein
    Expression System: E.coli

    Reinheit

    > 95 % pure
  • Applikationshinweise

    Prealbumin protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Supplied as a liquid in PBS, pH 7.4, containing 10 % glycerol.

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    RT/-20 °C

    Informationen zur Lagerung

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target

    TTR (Transthyretin (TTR))

    Hintergrund

    Prealbumin, also known as Transthyretin, is a tetrameric human plasma protein that is synthesized mainly in the liver. This protein transports the thyroid hormone thyroxine (T4) and retinol (Vitamin A). It is the best indicator of protein-energy malnutrition because it has a circulating half life of 2 days and responds rapidly to changes in nutritional status. Also point-mutations of its gene are known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC). Recombinant human Prealbumin was expressed in E. coli and purified by using conventional chromatography.
    Alternative Names: Amyloidosis I protein, TBPA protein, HsT2651 protein, Transthyretin protein, Prealbumin amyloidosis type I protein, Amyloid polyneuropathy protein, Senile systemic amyloidosis protein, ATTR protein, Dysprealbuminemic euthyroidal hyperthyroxinemia protein, TTR protein, PALB protein, Dystransthyretinemic hyperthyroxinemia protein, TTR protein.

    Molekulargewicht

    13.8 kDa (128 AA)
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