Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 530-826) Peptid
HIF1A
Reaktivität: Human
Wirt: Escherichia coli (E. coli)
SDS
Dithiothreitol (DTT)
1 image
Produktnummer ABIN934906
602,66 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 20 bis 27 Werktagen
Kurzübersicht für Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 530-826) Peptid (ABIN934906)
Target
HIF1A
(Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
Spezies
Human
Quelle
Escherichia coli (E. coli)
Applikation
SDS-PAGE (SDS)
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Protein-Typ
- Recombinant
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Protein Region
- AA 530-826
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Sequenz
- MEFKLELVEK LFAEDTEAKN PFSTQDTDLD LEMLAPYIPM DDDFQLRSFD QLSPLESSSA SPESASPQST VTVFQQTQIQ EPTANATTTT ATTDELKTVT KDRMEDIKIL IASPSPTHIH KETTSATSSP YRDTQSRTAS PNRAGKGVIE QTEKSHPRSP NVLSVALSQR TTVPEEELNP KILALQNAQR KRKMEHDGSL FQAVGIGTLL QQPDDHAATT SLSWKRVKGC KSSEQNGMEQ KTIILIPSDL ACRLLGQSMD ESGLPQLTSY DCEVNAPIQG SRNLLQGEEL LRALDQVN
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Produktmerkmale
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Purified recombinant Human Hif1 a? protein
Expression System: E.coli
The recombinant protein appeared as a 40 kDa band on SDS-PAGE. -
Reinheit
- > 95 % pure
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Applikationshinweise
- Hif1-alpha protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris-HCl, pH7.5, containing 0 mM DTT.
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Konservierungsmittel
- Dithiothreitol (DTT)
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Vorsichtsmaßnahmen
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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Informationen zur Lagerung
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
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Hintergrund
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Hypoxia-inducible factor-1 (HIF-1), identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. HIF-1 is a heterodimer composed of HIF-1 beta subunit and one of three subunits (Hif-1alpha, Hif-2alpha or Hif-3alpha). The activation of Hif-1 alpha is closely associated with a variety of tumors and oncogenic pathways. Hif-1 alpha consists of DNA binding domain (DBD domain), Dimerization domain and C-terminal regulatiory domains, including two transactivation domains (TAD), an oxygen-dependent degradation(ODD) domain, and inhibitory domains. Hif-1 alpha (530-826 residues) contains two TAD and inhibitory domain. Recombinant Hif-1 alpha (530-826 residues) was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Hifa-1 protein, Hif1a, HIF 1A protein, Hifa 1 protein, ARNT interacting protein protein, MOP1 protein, HIF 1alpha protein, bHLHe78 protein, Hif-1 alpha (530-826 aa) protein, HIF-1 alpha protein, Member of PAS protein 1 protein, Hifa-1, Hypoxia-inducible factor-1a Basic helix loop helix PAS protein MOP1 protein, MOP 1 protein, Member of the PAS Superfamily 1 protein, PASD8 protein, Hypoxia inducible factor 1 alpha isoform I.3 protein, Basic-helix-loop-helix-PAS protein MOP1 protein, Hypoxia-inducible factor 1 alpha protein, HIF1A protein, HIF1 alpha protein, PASD 8 protein, , Member of PAS protein 1 protein, Member of PAS superfamily 1 protein, Hifa 1, ARNT-interacting protein protein, Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor protein, Hypoxia inducible factor 1 alpha subunit protein, HIF1 A protein, Hypoxia inducible factor 1 alpha protein -
Molekulargewicht
- 32.8 kDa (298 AA)
Target
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