RXRalpha protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Supplied as a liquid in 20 mM Tris-HCl, pH7.5, containing 0.1 M NaCl, and 0 mM beta-Mercaptoethanol.
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
RT/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
Target
Retinoid X Receptor alpha (RXRA)
(Retinoid X Receptor, alpha (RXRA))
Hintergrund
The retinoid X receptor (RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors (RAR), thyroid hormone receptors (TR), vitamin D receptors and peroxisome proliferators-activated receptors (PPAR). The RXR family includes three difference isoforms, RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms (RXR alpha1, RXR alpha2). The DNA binding domain of RXR (111-228aa) was over expressed in E. coli and purified by using conventional column chromatography techniques. Alternative Names: RXR-alpha protein, Nuclear receptor subfamily 2 group B member 1 protein, RXRA protein, RXRalpha1 protein, NR2B1 protein, Retinoid X receptor alpha protein, MGC102720 protein, Retinoic acid receptor RXR alpha protein, Retinoid x receptor protein, RXRA1, RXR alpha1 protein, FLJ16020 protein, Retinoic acid receptor RXR-alpha protein, FLJ16733 protein