Purified recombinant Hepatitis C Virus NS3 protein Expression System: E.coli
Aufreinigung
Proprietary chromatographic technique
Reinheit
> 90 % pure
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
20 mM Tris-HCl, pH 8.0, with 20 mM beta mercaptoethanol.
Handhabung
Avoid repeated freeze/thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
HCV NS3
(Hepatitis C Virus NS3 (HCV NS3))
Substanzklasse
Viral Protein
Hintergrund
HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). Alternative Names: HCV NS3 protein, HCV protein, Hep C protein, Hepatitis C protein, HCV Recombinant protein, HCV NS3 Genotype-1a protein, HCV NS3 Genotype 1a protein