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BUD31 Homolog (BUD31) Peptid

BUD31 WB
Produktnummer ABIN925006
  • Target Alle BUD31 Produkte
    BUD31 (BUD31 Homolog (BUD31))
    Applikation
    Western Blotting (WB)
  • Applikationshinweise
    For use with EDG-2 (CT) polyclonal antibody ABIN187787. Incubate antibody neat with at least a 50 fold stoichiometric excess of blocking peptide at 37°C for 20 min. (molecular weights of peptide and antibody are ~2.5 kDa and ~160 kDa, respectively). Antibody can then be diluted to a concentration suitable for Western blot.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    50 µg provided in PBS at 1 mg/ml.
    Lagerung
    -20 °C
  • Target
    BUD31 (BUD31 Homolog (BUD31))
    Synonyme
    Cwc14 Peptide, EDG-2 Peptide, EDG2 Peptide, G10 Peptide, YCR063W Peptide, fSAP17 Peptide, g10l Peptide, zgc:110615 Peptide, CWC14 Peptide, DDBDRAFT_0190998 Peptide, DDBDRAFT_0233523 Peptide, DDB_0190998 Peptide, DDB_0233523 Peptide, bud31 Peptide, Edg2 Peptide, C77604 Peptide, g10 Peptide, c77604 Peptide, BUD31 homolog Peptide, BUD31 homolog (S. cerevisiae) Peptide, protein BUD31 homolog Peptide, U2 snRNP complex subunit BUD31 Peptide, U2 snRNP complex subunit Peptide, hypothetical protein Peptide, BUD31 homolog (yeast) Peptide, BUD31 homolog L homeolog Peptide, maternal g10 transcript Peptide, Protein BUD31 homolog Peptide, BUD31 Peptide, bud31 Peptide, Bud31 Peptide, bud31.L Peptide, LOC5569643 Peptide, CC1G_08861 Peptide, bud-31 Peptide, LOC109464260 Peptide, LOC108703088 Peptide
    Hintergrund
    Blocking peptide for use in Western blotting with anti-EDG-2 (CT) (ABIN187787). Endothelial cell differentiation gene-2 (EDG-2) receptor is a high affinity receptor for lysophosphatidic acid (LPA). EDG-2, also known as lysopholipid receptor A1, Vzg-1, mrec1.3 or GPCR26, like all other EDG receptors, couple multiple (3 or more) types of G proteins and transduce decreases in c[AMP]i through Gi and increases in [Ca 2+ ]i by augmenting phos- pholipase C through Gq/11 and beta/gamma dimmers and by induction of PI3 kinase, p125 FAK, phospholipase D by activating rho through G12/13. Human EDG-2 is present in high levels on oligodendrocytes and certain human malignant T cell lines. EDG-2 receptors (with EDG-4) may play a role in protecting cardiomyocytes from apoptosis induced by hypoxia and andrenergic stimulation.
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