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Vesicle-Associated Membrane Protein 7 (VAMP7) (C-Term) Peptid

VAMP7 Reaktivität: Human, Maus Wirt: Synthetic BP, WB
Produktnummer ABIN8115713
168,15 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen

Kurzübersicht für Vesicle-Associated Membrane Protein 7 (VAMP7) (C-Term) Peptid (ABIN8115713)

Target

VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

Spezies

Human, Maus

Quelle

  • 5
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Verwendungszweck

    Vamp7 Peptide - C-terminal region

    Sequenz

    DELKGIMVRN IDLVAQRGER LELLIDKTEN LVDSSVTFKT TSRNLARAMC
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Kommentare

    This is a synthetic peptide designed for use in combination with anti-Vamp7 Antibody (ARP47593_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Buffer

    Lyophilized powder

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
  • Target

    VAMP7 (Vesicle-Associated Membrane Protein 7 (VAMP7))

    Hintergrund

    Background Information: Vamp7 is involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Vamp7 is required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.Vamp7 is required for calcium regulated lysosomal exocytosis. Vamp7 is involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi.Vamp7 is required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Vamp7 is also required for focal exocytosis of late endocytic vesicles during phagosome formation.

    Alternative Symbols: Sybl1, TI-VAMP, VAMP-7

    Molekulargewicht

    25kDa

    Gen-ID

    20955

    NCBI Accession

    NP_035645

    UniProt

    P70280
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