Uracil-DNA Glycosylase (UNG) (C-Term) Peptid
Kurzübersicht für Uracil-DNA Glycosylase (UNG) (C-Term) Peptid (ABIN8115516)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Verwendungszweck
- UNG Peptide - C-terminal region
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Sequenz
- GWAKQGVLLL NAVLTVRAHQ ANSHKERGWE QFTDAVVSWL NQNSNGLVFL
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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This is a synthetic peptide designed for use in combination with anti-UNG Antibody (ARP61205_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UNG (Uracil-DNA Glycosylase (UNG))
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Hintergrund
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Background Information: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Alternative Symbols: DGU, DKFZp781L1143, HIGM4, UDG, UNG1, UNG15, UNG2
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Molekulargewicht
- 34kDa
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Gen-ID
- 7374
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NCBI Accession
- NP_550433
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UniProt
- P13051
Target
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