Unc-13 Homolog B (UNC13B) (Middle Region) Peptid
UNC13B
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN8115449
168,15 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 6 bis 9 Werktagen
Kurzübersicht für Unc-13 Homolog B (UNC13B) (Middle Region) Peptid (ABIN8115449)
Target
UNC13B
(Unc-13 Homolog B (UNC13B))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Verwendungszweck
- UNC13B Peptide - middle region
-
Sequenz
- SYDLDYPERR AISPTSSSRY GSSCNVSQGS SQLSELDQYH EQDDDHRETD
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- UNC13B (Unc-13 Homolog B (UNC13B))
-
Hintergrund
-
Background Information: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Alternative Symbols: UNC13, MUNC13, Unc13h2
-
Molekulargewicht
- 181 kDa
-
Gen-ID
- 10497
-
NCBI Accession
- NP_006368
-
UniProt
- O14795
Target
-
Sie sind hier:
