Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) Peptid
SIGIRR
Wirt: Synthetic
BP, IHC, WB
Produktnummer ABIN8111779
168,15 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 6 bis 9 Werktagen
Kurzübersicht für Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR) Peptid (ABIN8111779)
Target
SIGIRR
(Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
-
-
Verwendungszweck
- SIGIRR Peptide
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
This is a synthetic peptide designed for use in combination with anti-SIGIRR antibody ( ARP49664_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR))
-
Hintergrund
-
Background Information: SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through a TIR-TIR domain interaction with TLR4. Through its extracellular domain it interferes with the heterodimerization of Il1R1 and IL1RAP.
Alternative Symbols: MGC110992, TIR8
-
Molekulargewicht
- 25kDa
-
Gen-ID
- 59307
-
UniProt
- Q6IA17
Target
-
Sie sind hier:
